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NIKE FREE 5.0 SWIFT 女子赤足跑步鞋 349裸
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【名称】:耐克/NIKE&FREE 5.0 SWIFT 女子赤足跑步鞋&【品牌】:耐克/NIKE【货号】:【颜色】:如图【材质】:织物【尺码】:36、36.5、37.5、38、38.5、39、40码(下单时可选的尺码说明还有,不可选的尺码说明已售完)【主力推荐】:&Nike Free 5.0 Swift 女子跑步鞋结合革新外底与可提供六向移动的弯曲凹槽精心打造,实现全方位的足部移动和极致自然的穿着体验,令足部保持宛如赤足般的舒适感受。其他细节轻盈的网布鞋面,打造出色透气性Flywire 技术动态贴合,稳固锁定无缝内靴为双足提供柔软且舒适的贴合Phylon 中底搭配深切弯曲凹槽,提供轻盈的缓震效果,缔造舒适自然的运动感受六边形弯曲凹槽具有六向移动性能,为您带来超凡灵活性匠心排布的橡胶凸耳,提升耐磨性本店商品均为专柜正品,本店现货实拍,承诺假一赔百,决不食言。有意者请联系:&QQ:&&旺旺ID:tanggoodboy加入QQ群:,享会员专属优惠扫描以下二维码,关注主力团微信(微信号:zhulituan)获取更多产品资讯
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555人参加识货团购268.00元932人参加识货团购439.00元561人参加识货团购558.00元194人参加识货团购550.00元506人参加识货团购568.00元688人参加识货团购499.00元148人参加识货团购199.00元90人参加识货团购468.00元70人参加识货团购69.00元673人参加识货团购780.00元217人参加识货团购199.00元356人参加识货团购99.00元BACKGROUND: Oral and intravenous formulations of ciprofloxacin have established Nike Free 5.0 efficacy and safety profiles in respiratory infections. A dry powder for inhalation (DPI) that uses Novartis\' PulmoSphere(TM) technology has been developed to deliver high concentrations of ciprofloxacin to the lung with low systemic exposure using a portable and convenient passive dry powder inhaler (Novartis\' T-326 inhaler).OBJECTIVES: The primary objective was to investigate the safety and tolerability of ciprofloxacin DPI in healthy male subjects, with a secondary objective to investigate the pharmacokinetics of ciprofloxacin after ciprofloxacin DPI administration.METHODS: This was a phase I, single-dose, single-site, randomized, single-blind, placebo-controlled, crossover study conducted in the hospital setting. Subjects were followed up for safety for approximately 2 weeks. Six healthy male subjects, aged 27-42 years with no history of pulmonary disease, repeated bronchitis or respiratory allergies were enrolled. In randomized order and separated by a 1-week washout period, subjects inhaled a single dose of ciprofloxacin DPI 32.5 mg or placebo from the T-326 inhaler. Primary safety parameters included vital signs, electrocardiogram, laboratory tests, adverse events and lung function (total specific resistance, thoracic gas volume and forced expiratory volume in 1 s). Plasma concentration-time data were used to calculate pharmacokinetic parameters.RESULTS: Ciprofloxacin DPI was well tolerated with no clinically relevant adverse effects on lung function. Estimates of lung deposition derived from physiology-based pharmacokinetic modelling suggest that approximately 40 % of the total dose of ciprofloxacin DPI reached the trachea/bronchi and alveolar space. Systemic ciprofloxacin was detected soon after inhalation [peak concentration in plasma (C(max)) nike Free Switzerland 56.42 μg/L, median time to C max 0.625 h], but total systemic exposure was nike Free Run 2 minimal (area under the nike Free Run Switzerland plasma concentration-time curve 354.4 μg·h/L). Terminal elimination half-life (9.5 h), apparent total clearance from plasma after non-intravenous administration (91.7 nike Free Trainer 5.0 L/h) and apparent volume of distribution (1,262 L) data suggest that elimination from the respiratory tract was prolonged.CONCLUSIONS: In healthy subjects, ciprofloxacin DPI was well tolerated, delivered ciprofloxacin to the lungs and resulted in minimal systemic exposure, allowing further investigation of its clinical use for the management of specific, chronic infections in pulmonary diseases.您的购物车没有任何商品
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